The blast area was also meters away from the site of another deadly truck bombing in May that killed up to 150 people.
The target of the attack was not immediately clear but as well as foreign embassies, the area contains a defense ministry department dealing with foreign relations and several private businesses, including a barber and a travel agency.
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Alcohol does not appear to be an issue in the crash and police are investigating other possible contributing factors. The six other people in the buggy were taken to the hospital with life threatening injuries.
"There were a number of dead bodies and wounded victims lying around", said Ghulam Hazrat, who witnessed the attack.
Islamic State claimed responsibility for the attack. "There were no casualties to our personnel", Waziri said. "It was a frightful scene", an eyewitness told TOLOnews.
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AFP reporters heard a loud explosion around 4:00pm (1130 GMT) just as workers would have been leaving their offices to go home, followed by the sirens of emergency services. According to the television channel, a suicide bomber blew himself up in Kabul's diplomatic quarters Wazir Akbar Khan.
Over the weekend Taliban insurgents, some wearing night-vision goggles, killed 22 Afghan policemen in separate attacks on checkpoints.
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I don't think it will seam as much but still there should be some help and then dew later on in the game. We had to be at our best to win.
Last week a suicide bomber detonated his explosives-laden care near the Afghan military academy in the capital city, killing 15 cadets and wounding several others.